MYELOID SARCOMA, A RARITY OF THE HEAD AND NECK REGION - A CASE REPORT

Madhusudhan KRISHNAMOORTHY, Bee Sun LEE, Sellymiah BINTI ADZMAN, Shahrul BIN HITAM

Abstract


Myeloid sarcoma is a rare disease, where a mass (tumour) of either myeloblasts or immature myeloid cells conglomerate in extramedullary anatomic sites. It may arise de-novo or it may present in association with acute myeloid leukemia. It can also occur in patients with myelodysplastic syndromes, myeloproliferative disorders, and as blast transformation in myeloproliferative neoplasia. Myeloid sarcoma of the head and neck area can pose a diagnostic challenge because of the low frequency of occurrence, and the vast diversity of tumours occurring from multiple lineages in this anatomic region. This can lead to a broad spectrum of various differential diagnoses. Therefore, a high index of suspicion is required when dealing with a possible case of myeloid sarcoma, as it is a time sensitive diagnosis with various diagnostic dilemmas. Here, we report an example, a case of tonsillar myeloid sarcoma. We wish to highlight the investigations that helped us procure this diagnosis in a timely manner.

Keywords


Myeloid sarcoma; tonsils; acute myeloid leukemia; lymphoid hypertrophy

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DOI: http://dx.doi.org/10.15342%2Fijms.v4ir.169

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Université Mohammed VI des Sciences de la Santé