Paradoxical Reactions During Antituberculosis Therapy - A Single-Center Prospective Analysis
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Keywords

Paradoxical reaction
Antituberculosis therapy
SHIV-negative

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How to Cite

1.
Hammi S, Zemed N, Bouti K, Bourkadi JE. Paradoxical Reactions During Antituberculosis Therapy - A Single-Center Prospective Analysis. Integr J Med Sci [Internet]. 2015 Jan. 30 [cited 2024 Mar. 29];2:32-5. Available from: https://mbmj.org/index.php/ijms/article/view/24

Abstract

Background:  Paradoxical reactions during anti-TB treatment represent a real challenge to pneumo-phthisiologists and require a high index of suspicion. It has been suggested that this reaction during appropriate treatment is common and severe in HIV-negative individuals. Our objective was to determine the frequency of paradoxical reactions and their associated features. Method: A prospective study was undertaken in a population of HIV-TB+ patients to determine the frequency of paradoxical reactions and their associated features. Results: Paradoxical reactions occurred in 1.5% of all our hospital’s TB patients. Conclusion: Paradoxical reactions during anti-TB treatment is common in HIV-uninfected individuals and must be considered after careful exclusion of medication non-adherence, other infections, development of resistance, and other similar conditions.

https://doi.org/10.15342/ijms.v2i2.75
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Copyright (c) 2015 Sanae Hammi et al.

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