Breast cancer skin recurrence: a comprehensive review on pathogenesis, treatment, and prognosis

Georgios Pechlivanides, Vassilios Kalles, Georgios Boutsikos, Lazaros Papadopoulos

Abstract


The manifestation of breast cancer recurrence in the form of skin lesions has always been a frustration for both the oncologist and the breast surgeon. Surgeons are asked to treat a recurrent disease that is yet unclear whether it represents disseminated or local disease. Cancer cells are found both in the lymphatics as well as the blood vessels, but, on the other hand, skin recurrence usually does not respond well to the current forms of systemic treatment, and it often needs some form of local treatment for symptom control.


Keywords


breast cancer, cutaneous metastases, skin metastases

References


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DOI: http://dx.doi.org/10.15342%2Fijms.v6ir.299

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