Abstract
Cognitive decline is a growing medical concern. It includes age-related cognitive decline, mild cognitive impairment, and dementia. Dementia results in considerable dysfunction in life and is associated with an increase in mortality. Since there is no cure at this time, attention is being increasingly directed towards prevention. Lifestyle factors, such as smoking, alcoholism, physical inactivity, poor diet, improper sleep, and loneliness are repeatedly being recognized as modifiable factors that can reduce cognitive decline. This manuscript briefly reviews the lifestyle-cognition relationship.
References
Chaves AS, dos Santos AM, Soares de Britto E, Alves MT, Filho NS. Association between cognitive decline and the quality of life of hypertensive elderly individuals. Rev Bras Geriatr Gerontol. 2015;18(3):545–56. https://doi.org/10.1590/1809-9823.2015.14043
Singh-Manoux A, Kivimaki M, Glymour MM, Elbaz A, Berr C, Ebmeier KP, et al. Timing of onset of cognitive decline: results from Whitehall II prospective cohort study. BMJ. 2012 Jan 5;344:d7622. https://doi.org/10.1136/bmj.d7622
Lin PJ, Zhong Y, Fillit HM, Chen E, Neumann PJ. Medicare expenditures of Individuals with Alzheimer’s Disease and related dementias or mild cognitive impairment before and after diagnosis. J Am Geriatr Soc. 2016 Aug;64(8):1549-57. https://doi.org/10.1111/jgs.14227
Roberts R, Knopman DS. Classification and Epidemiology of MCI. Clin Geriatr Med. 2013 Nov;29(4):753-72. https://doi.org/10.1016/j.cger.2013.07.003
Petersen RC. Clinical practice. mild cognitive impairment. N Engl J Med. 2011 Jun 9;364(23):2227-34. https://doi.org/10.1056/nejmcp0910237
Draper B, Cations M, White F, Trollor J, Loy C, Brodaty H, et al. Time to diagnosis in young-onset dementia and its determinants: The inspired study. Int J Geriatr Psychiatry. 2016 Nov;31(11):1217-1224. https://doi.org/10.1002/gps.4430
Prince M, Ali GC, Guerchet M, Prina AM, Albanese E, Wu YT. Recent global trends in the prevalence and incidence of dementia, and survival with dementia. Alzheimers Res Ther. 2016 Jul 30;8(1):23. https://doi.org/10.1186/s13195-016-0188-8
World Health Organisation. Global Action Plan on the Public Health Response to Dementia 2017–2020; World Health Organisation: Geneva, Switzerland, 2017.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th ed.; American Psychiatric Association: Washington, DC, USA, 2013.
Galvin JE, Sadowsky CH; NINCDS-ADRDA. Practical guidelines for the recognition and diagnosis of dementia. J Am Board Fam Med. 2012 May-Jun;25(3):367-82. https://doi.org/10.3122/jabfm.2012.03.100181
Landeiro F, Mughal S, Walsh K, Nye E, Morton J, Williams H, et al. ROADMAP consortium. Health-related quality of life in people with predementia Alzheimer's disease, mild cognitive impairment or dementia measured with preference-based instruments: a systematic literature review. Alzheimers Res Ther. 2020 Nov 18;12(1):154. https://doi.org/10.1186/s13195-020-00723-1
Dewey ME, Saz P. Dementia, cognitive impairment and mortality in persons aged 65 and over living in the community: A systematic review of the literature. Int J Geriatr Psychiatr. 2001;16:751–761. https://doi.org/10.1002/gps.397
Calabrese M, Poretto V, Favaretto A, Alessio S, Bernardi V, Romualdi C, et al. Cortical lesion load associates with progression of disability in multiple sclerosis. Brain 2012;135:2952–2961. https://doi.org/10.1093/brain/aws246
Campbell S, Manthorpe J, Samsi K, Abley C, Robinson L, Watts S, et al. Living with uncertainty: Mapping the transition from pre-diagnosis to a diagnosis of dementia. J Aging Stud. 2016 Apr;37:40-7. https://doi.org/10.1016/j.jaging.2016.03.001
Kivipelto M, Mangialasche F, Ngandu T. Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease. Nat Rev Neurol. 2018 Nov;14(11):653-666. https://doi.org/10.1038/s41582-018-0070-3
Gluckman TJ, Kovacs RJ, Stone NJ, Damalas D, Mullen JB, Oetgen WJ. The ASCVD risk estimator app: from concept to the current state. J Am Coll Cardiol. 2016 Jan 26;67(3):350-2. https://doi.org/10.1016/j.jacc.2015.10.068
Shiels PG, Buchanan S, Selman C, Stenvinkel P. Allostatic load and ageing: linking the microbiome and nutrition with age-related health. Biochem Soc Trans. 2019 Aug 30;47(4):1165-1172. https://doi.org/10.1042/bst20190110
Li Y, Schoufour J, Wang DD, Dhana K, Pan A, Liu X, et al. Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study. BMJ. 2020 Jan 8;368:l6669. https://doi.org/10.1136/bmj.l6669
Loef M, Walach H. The combined effects of healthy lifestyle behaviors on all cause mortality: a systematic review and meta-analysis. Prev Med 2012;55:163-70. https://doi.org/10.1016/j.ypmed.2012.06.017
Mokdad AH, Forouzanfar MH, Daoud F, Mokdad AA, El Bcheraoui C, Moradi-Lakeh M, et al. Global burden of diseases, injuries, and risk factors for young people’s health during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2016 Jun 11;387(10036):2383-401. https://doi.org/10.1016/S0140-6736(16)00648-6
Li Y, Pan A, Wang DD, Liu X, Dhana K, Franco OH, et al. Impact of Healthy Lifestyle Factors on Life Expectancies in the US Population. Circulation. 2018;138:345–355. https://doi.org/10.1161/circulationaha.117.032047
O'Doherty MG, Cairns K, O'Neill V, Lamrock F, Jørgensen T, Brenner H, et al. Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES). Eur J Epidemiol. 2016 May;31(5):455-68. https://doi.org/10.1007/s10654-015-0112-8
https://www.who.int/ageing/publications/global_health.pdf Accessed January 8, 2021.
Huang Z, Guo Y, Ruan Y, Sun S, Lin T, Ye J, et al. Associations of Lifestyle Factors With Cognition in Community-Dwelling Adults Aged 50 and Older: A Longitudinal Cohort Study. Front Aging Neurosci. 2020 Nov 9;12:601487. https://doi.org/10.3389/fnagi.2020.601487
Newhouse P, Kellar K, Aisen P, White H, Wesnes K, Coderre E, ET AL. Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial. Neurology. 2012 Jan 10;78(2):91-101. https://doi.org/10.1212/WNL.0b013e31823efcbb
Millan MJ, Agid Y, Brüne M, Bullmore ET, Carter CS, Clayton NS, et al. Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nat Rev Drug Discov. 2012 Feb 1;11(2):141-68. http://dx.doi.org/10.1038/nrd3628
de Leon J, Diaz FJ. A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors. Schizophr Res. 2005 Jul 15;76(2-3):135-57. https://doi.org/10.1016/j.schres.2005.02.010
Besson M, Forget B. Cognitive dysfunction, affective states, and vulnerability to nicotine addiction: A multifactorial perspective. Front Psychiatry. 2016;7:160. http://dx.doi.org/10.3389/fpsyt. 2016.00160
Newhouse PA, Potter A, Singh A. Effects of nicotinic stimulation on cognitive performance. Curr Opin Pharmacol. 2004 Feb;4(1):36-46. https://doi.org/10.1016/j.coph.2003.11.001
Hill RD, Nilsson LG, Nyberg L, Bäckman L. Cigarette smoking and cognitive performance in healthy Swedish adults. Age Ageing. 2003 Sep;32(5):548-50. https://doi.org/10.1093/ageing/afg067
Zhan Y, Fang F. Smoking and amyotrophic lateral sclerosis: a mendelian randomization study. Ann Neurol. 2019;85(4):482-484. https://doi.org/10.1002/ana.25443
Durazzo TC, Mattsson N, Weiner MW. Alzheimer’s Disease Neuroimaging Initiative. Smoking and increased Alzheimer’s disease risk: a review of potential mechanisms. Alzheimers Dement. 2014;10(3)(suppl):S122-S145. https://doi.org/10.1016/j.jalz.2014.04.009
Khan U, Porteous L, Hassan A, Markus HS. Risk factor profile of cerebral small vessel disease and its subtypes. J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):702-6. https://doi.org/10.1136/jnnp.2006.103549
Anstey KJ, von Sanden C, Salim A, O'Kearney R. Smoking as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies. Am J Epidemiol. 2007 Aug 15;166(4):367-78. https://doi.org/10.1093/aje/kwm116
Tyas SL, White LR, Petrovitch H, Webster Ross G, Foley DJ, Heimovitz HK, et al. Mid-life smoking and late-life dementia: the honolulu-asia aging study. Neurobiol Aging. 2003 Jul-Aug;24(4):589-96. https://doi.org/10.1016/s0197-4580(02)00156-2
Liu Y, Li H, Wang J, Xue Q, Yang X, Kang Y, et al. Association of Cigarette Smoking With Cerebrospinal Fluid Biomarkers of Neurodegeneration, Neuroinflammation, and Oxidation. JAMA Netw Open. 2020 Oct 1;3(10):e2018777. https://doi.org/10.1001/jamanetworkopen.2020.18777
Karama S, Ducharme S, Corley J, Chouinard-Decorte F, Starr JM, Wardlaw JM, et al. Cigarette smoking and thinning of the brain’s cortex. Mol Psychiatry. 2015 Jun;20(6):778-85. https://doi.org/10.1038/mp.2014.187
He F, Li T, Lin J, Li F, Zhai Y, Zhang T, et al. Passive Smoking Exposure in Living Environments Reduces Cognitive Function: A Prospective Cohort Study in Older Adults. Int J Environ Res Public Health. 2020 Feb 21;17(4):1402. https://doi.org/10.3390/ijerph17041402
Velusami D, Venkatesh S, Soundariya K. Effect of smoking on neurocognitive function. Int J Basic Appl Physiol. 2016;5(1).
Mons U, Schöttker B, Müller H, Kliegel M, Brenner H. History of lifetime smoking, smoking cessation and cognitive function in the elderly population. Eur J Epidemiol. 2013 Oct;28(10):823-31. https://doi.org/10.1007/s10654-013-9840-9
United States Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality (2012). National survey on drug use and health, 2012 [Data set]. National survey on drug use and health (NSDUH) series. ICPSR—Interuniversity Consortium for Political and Social Research. https://doi.org/10.3886/ICPSR34933.v3
Wood AM, Kaptoge S, Butterworth AS, Willeit P, Warnakula S, Bolton T, et al. Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group . Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. Lancet. 2018;391(10129):1513-1523. https://doi.org/10.1016/S0140-6736(18)30134-X
Xu W, Wang H, Wan Y, Tan C, Li J, Tan L, et al. Alcohol consumption and dementia risk: A dose-response meta-analysis of prospective studies. Eur J Epidemiol. 2017;32(1):31–42. https://doi.org/10.1007/s10654-017-0225-3
Cheng C, Huang CL, Tsai CJ, Chou PH, Lin CC, Chang CK. Alcohol-Related Dementia: A Systemic Review of Epidemiological Studies. Psychosomatics. 2017 Jul-Aug;58(4):331-342. https://doi.org/10.1016/j.psym.2017.02.012
Clark DB, Thatcher DL, Tapert SF. Alcohol, psychological dysregulation, and adolescent brain development. Alcohol Clin Exp Res. 2008 Mar;32(3):375-85. https://doi.org/10.1111/j.1530-0277.2007.00601.x
Oscar-Berman M, Marinkovic K. Alcohol: Effects on neurobehavioral functions and the brain. Neuropsychol. Rev. 2007;17:239–257. https://doi.org/10.1007/s11065-007-9038-6
Römer P, Mathes B, Reinelt T, Stoyanova P, Petermann F, Zierul C. Systematic review showed that low and moderate prenatal alcohol and nicotine exposure affected early child development. Acta Paediatr. 2020, 109, 2491–2501. https://doi.org/10.1111/apa.15453
Cai H, Li G, Hua S, Liu Y, Chen L. Effect of exercise on cognitive function in chronic disease patients: a meta-analysis and systematic review of randomized controlled trials. Clin Interv Aging. 2017;12:773-783. https://doi.org/10.2147/CIA.S135700
Yu JT, Xu W, Tan CC, Andrieu S, Suckling J, Evangelou E, et al. Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. J Neurol Neurosurg Psychiatry. 2020;91(11):1201-1209. https://doi.org/10.1136/jnnp-2019-321913
Huang Z, Guo Y, Ruan Y, Sun S, Lin T, Ye J, et al. Associations of Lifestyle Factors With Cognition in Community-Dwelling Adults Aged 50 and Older: A Longitudinal Cohort Study. Front Aging Neurosci. 2020 Nov 9;12:601487. https://doi.org/10.3389/fnagi.2020.601487
Sofi F, Valecchi D, Bacci D, Abbate R, Gensini GF, Casini A, et al. Physical activity and risk of cognitive decline: a meta-analysis of prospective studies. J Intern Med. 2011 Jan;269(1):107-17. https://doi.org/10.1111/j.1365-2796.2010.02281.x
Gehlich KH, Beller J, Lange-Asschenfeldt B, Köcher W, Meinke MC, Lademann J. Fruit and vegetable consumption is associated with improved mental and cognitive health in older adults from non-Western developing countries. Public Health Nutr. 2019 Mar;22(4):689-696. https://doi.org/10.1017/s1368980018002525
Fieldhouse JLP, Doorduijn AS, de Leeuw FA, Verhaar BJH, Koene T, Wesselman LMP, et al. A Suboptimal Diet is Associated with Poorer Cognition: The NUDAD Project. Nutrients. 2020 Mar 6;12(3):703. https://doi.org/10.3390/nu12030703
Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS. Associations of vegetable and fruit consumption with age-related cognitive change. Neurology. 2006 Oct 24;67(8):1370-6. https://doi.org/10.1212/01.wnl.0000240224.38978.d8
van den Brink AC, Brouwer-Brolsma EM, Berendsen AAM, van de Rest O. The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer’s Disease—A Review. Adv Nutr. 2019 Nov 1;10(6):1040-1065. https://doi.org/10.1093/advances/nmz054
Fieldhouse JLP, Doorduijn AS, de Leeuw FA, Verhaar BJH, Koene T, Wesselman LMP, et al. A Suboptimal Diet is Associated with Poorer Cognition: The NUDAD Project. Nutrients. 2020;12(3):703. https://doi.org/10.3390/nu12030703
Fotuhi M, Mohassel P, Yaffe K. Fish consumption, long-chain omega-3 fatty acids and risk of cognitive decline or Alzheimer disease: A complex association. Nat Clin Pract Neurol. 2009 Mar;5(3):140-52. https://doi.org/10.1038/ncpneuro1044
Gehlich KH, Beller J, Lange-Asschenfeldt B, Köcher W, Meinke MC, Lademann J. Fruit and vegetable consumption is associated with improved mental and cognitive health in older adults from non-Western developing countries. Public Health Nutr. 2019 Mar;22(4):689-696. https://doi.org/10.1017/s1368980018002525
Pistollato F, Sumalla Cano S, Elio I, Masias Vergara M, Giampieri F, Battino M. Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease. Nutr Rev. 2016 Oct;74(10):624-34. https://doi.org/10.1093/nutrit/nuw023
van der Wurff ISM, Meyer BJ, de Groot RHM. Effect of Omega-3 Long Chain Polyunsaturated Fatty Acids (n-3 LCPUFA) Supplementation on Cognition in Children and Adolescents: A Systematic Literature Review with a Focus on n-3 LCPUFA Blood Values and Dose of DHA and EPA. Nutrients. 2020 Oct 12;12(10):3115. https://doi.org/10.3390/nu12103115
Bischof GN, Park DC. Obesity and aging: consequences for cognition, brain structure, and brain function. Psychosom Med. 2015 Jul-Aug;77(6):697-709. https://doi.org/10.1097/psy.0000000000000212
Monda V, La Marra M, Perrella R, Caviglia G, Iavarone A, Chieffi S, et al. Obesity and brain illness: from cognitive and psychological evidences to obesity paradox. Diabetes Metab Syndr Obes. 2017 Nov 21;10:473-479. https://doi.org/10.2147/dmso.s148392
Gottschling S, Ayonrinde O, Bhaskar A, Blockman M, D'Agnone O, Schecter D, et al. Safety Considerations in Cannabinoid-Based Medicine. Int J Gen Med. 2020 Dec 1;13:1317-1333.. https://doi.org/10.2147/ijgm.s275049
Bubu OM, Brannick M, Mortimer J, Umasabor-Bubu O, Sebastião YV, Wen Y, et al. Sleep, cognitive impairment, and Alzheimer’s disease: a systematic review and meta-analysis. Sleep. 2017 Jan 1;40(1). https://doi.org/10.1093/sleep/zsw032
Lara E, Caballero FF, Rico-Uribe LA, Olaya B, Haro JM, Ayuso-Mateos JL, et al. Are loneliness and social isolation associated with cognitive decline? Int J Geriatr Psychiatry. 2019 Nov;34(11):1613-1622. https://doi.org/10.1002/gps.5174
Baumeister RF, DeWall CN, Ciarocco NJ, Twenge JM. Social exclusion impairs self-regulation. J Pers Soc Psychol. 2005 Apr;88(4):589-604. https://doi.org/10.1037/0022-3514.88.4.589
Jaremka LM, Andridge RR, Fagundes CP, Alfano CM, Povoski SP, Lipari AM, et al. Pain, depression, and fatigue: loneliness as a longitudinal risk factor. Health Psychol. 2014 Sep;33(9):948-57. https://doi.org/10.1037/a0034012
Cacioppo JT, Ernst JM, Burleson MH, McClintock MK, Malarkey WB, Hawkley LC, et al. Lonely traits and concomitant physiological processes: the MacArthur social neuroscience studies. Int J Psychophysiol. 2000 Mar;35(2-3):143-54. https://doi.org/10.1016/s0167-8760(99)00049-5
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