Male Infertility - An Analysis in a Low Resource Setting


Luteinising Hormone(LH)
Follicle stimulating hormone(FSH)
Serum Total Testosterone(TT)
Testicular Microlithiasis(TM)


How to Cite

Jain D, Jain S. Male Infertility - An Analysis in a Low Resource Setting. Integr J Med Sci [Internet]. 2021 Mar. 4 [cited 2021 Oct. 26];8. Available from:


Purpose The prevalence of male subfertility is increasing among couples seeking fecundity in recent  years. A prospective study was carried out in a gynaecological outpatient ,  to determine the benefit of a low cost algorithm for diagnosis of adult males with suboptimal semen parameters. Materials and Methods Twenty nine males, who had a sperm  concentration less than 15 million/ml were considered in the study. The cost of diagnosis was kept low ; not exceeding 150 US dollars. A similar  algorithm of investigation was followed for all patients and medical treatment provided as per treatment guidelines .Results A confirmed etiology could be determined in 9 patients , while a probable diagnosis was suggested in 17 males.  Endocrino-metabolic causes were the most important etiological factors in our Indian population . Lifestyle diseases like obesity , insulin resistance were  prominently found in the suspected  acquired hypogonadotropic hypogonadism group..Medical treatment was provided to 24 males, and 64% showed good improvement in seminal count , after 3 months of therapy. Only  selected patients were referred to higher teritiary centres, for specific interventions like sperm retrieval techniques , intracytoplasmic sperm injection of the female partner. Conclusion This study  proves  that male subfertility can be managed in a low resource semiurban centre, with the help of a simple algorithm with ease and proficiency,hence  reducing economic burden on these couples. Also, this analysis has helped us  to ascertain the relative propensity of  etiological factors  among  adult males with  infertility ,in  North India in the present  time.


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