A Retrospective Study of Microbial Profile of Head Injury and Stroke Patients Admitted in EMCH, Savar, Dhaka, Bangladesh


Microbial profile
Head injury
Stroke patient


How to Cite

Sahidullah Monsur SM, Bulbul Islam BI, Karim AB, Hasan A, Habib R, Reza M. A Retrospective Study of Microbial Profile of Head Injury and Stroke Patients Admitted in EMCH, Savar, Dhaka, Bangladesh. Integr J Med Sci [Internet]. 2022 Apr. 21 [cited 2024 Mar. 3];9. Available from: https://mbmj.org/index.php/ijms/article/view/663


Introduction: Many head injury patients have reduced consciousness, are prone to aspiration of oral secretions, and likely develop pneumonia. Respiratory tract infection (RTI), especially pneumonia, is a very common disease in neurosurgical intensive care units (NSICU).
Objective: This study evaluates the microbial profile of head injury and stroke patients admitted to Enam Medical College & Hospital (EMCH), Savar, Dhaka, Bangladesh.
Methods: It was a retrospective study conducted at EMCH, Savar, Bangladesh, from 2017 to 2021. A total of 46 patients admitted with a head injury and stroke were enrolled in this study. Data were collected using a structured questionnaire containing all the variables of interest. Data were processed and analyzed with the help of the computer program SPSS for Windows version 25.
Results: This study sample consisted of 84.8% males and 15.2% females. The mean age was 42.54 ± 18.09 years. Pathogens found in culture samples were tracheal aspirate C/S (54.3%), urine C/S (26.1%), catheter tip C/S (13%), and the tip of the ET tube C/S (4.3%). The main attributed pathogens were Staphylococcus aureus (47.8%), Klebsiella spp. (37%), E. coli (32.6%), Streptococcus (2.2%), Acinetobacter spp. (2.2%), and Pseudomonas spp. (2.2%).
Conclusion: This study shows that Staphylococcus aureus, Klebsiella spp., and E. coli are the most common isolated pathogens. Therefore, detailed microbial profiles and antibiotic susceptibility testing are necessary for the prevention of pathogens and effective treatment.



Das J, Rajkumari S, Dangol S, Sapkota R, Mishra M. Bacteriological profile of endotracheal tube aspirates in head injury patients admitted in Neurosurgical Intensive Care Unit: a cross-sectional study from a tertiary care hospital of Central Nepal. Asia Pacific J Clinical Trials Nervous System Dis. 2019; 4(3):75-80.

Mandell LA, Niederman MS. Aspiration Pneumonia. N Engl J Med. 2019; 380: 651–663. https://doi.org/10.1056/nejmra1714562

Zhao J, Li L, Zhen N, Du L, Shan H, Yu Y, et al. Microbiology and Outcomes of Institutionalized Patients With Stroke-Associated Pneumonia: An Observational Cohort Study. Front Microbiol. 2021; 12:720051. https://dx.doi.org/10.3389%2Ffmicb.2021.720051

Wunderink RG, Waterer G. Advances in the causes and management of community acquired pneumonia in adults. BMJ. 2017 Jul 10;358:j2471. https://doi.org/10.1136/bmj.j2471

Morinaga Y, Take Y, Sasaki D, Ota K, Kaku N, Uno N, et al. Exploring the microbiota of upper respiratory tract during the development of pneumonia in a mouse model. PLoS One. 2019 Sep 27;14(9):e0222589. https://doi.org/10.1371/journal.pone.0222589

Lin P, Fu JX, Zhang HN. Analysis of pathogens, risk factors, and T lymphocyte levels in patients with pneumonia following a stroke. J Pathogen Biol. 2019; 14, 826–829.

Leone M, Bouadma L, Bouhemad B, Brissaud O, Dauger S, Gibot S. Hospital-acquired pneumonia in ICU. Anaesth Crit Care Pain Med. 2018 Feb;37(1):83-98. https://doi.org/10.1016/j.accpm.2017.11.006

Chandran RS, Sharma S, Rajmohan BP, Peethambaran AK. Epidemiology and microbiology of infections in traumatic brain injury patients. Global J Res Analys. 2017;6 (2):2277–8160.

Kishore AK, Vail A, Jeans AR, Chamorro A, Di Napoli M, Kalra L. Microbiological Etiologies of Pneumonia Complicating Stroke: a Systematic Review. Stroke. 2018 Jul;49(7):1602-1609. https://doi.org/10.1161/strokeaha.117.020250

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Copyright (c) 2021 Abu Tahir Moh’d Sahidullah Monsur, Kazi Shaha Bulbul Islam, A.K.M Bazlul Karim, Arif Hasan, Riad Habib, Mamun Reza


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