Remdesivir Research Progress: An Overview of the Emerging Evidence
PDF

Keywords

Remdesivir
Research progress
Covid 19

How to Cite

1.
Al Mosawi AJ. Remdesivir Research Progress: An Overview of the Emerging Evidence . Health Sci. [Internet]. 2020 Oct. 29 [cited 2022 May 16];. Available from: https://mbmj.org/index.php/hs/article/view/247

Abstract

There has been an increasing interest in remdesivir research within the scientific medical community because of the emerging evidence suggesting its beneficial role in patients with Covid‑19. Remdesivir which can be given intravenously and not orally has an anti-viral against several RNA viruses. The aim of this paper is to review remdesivir research progress.

https://doi.org/10.15342/hs.2020.247
PDF

References

Al-Mosawi AJ. Bat-Human Coronaviruses: A Global Health Problem and a Therapeutic Challenge. J Med Clin Case Rep. 2020; 2(2): 1-3. [Accessed 2022 Mar 23]. Available from: https://unisciencepub.com/storage/2020/05/Bat-Human-Coronaviruses-A-Global-Health-Problem-and-a-Therapeutic-Challenge.pdf

Al-Mosawi AJ. The Use of the Available Research Evidence to Crack the Padlock of Sars-CoV-2. J Virol Res Rep. 2020; 1 (1):1-8. [Accessed 2022 Mar 23]. Available from: https://www.joctn.com/index.php/jctn/article/view/8

Al-Mosawi AJ. Bat-human coronaviruses: Keys to the therapeutic challenge.1st ed., Saarbrücken; LAP Lambert Academic Publishing: 2020.

Al-Mosawi AJ. Bat-human Coronaviruses: Keys to The Therapeutic Challenge .1st ed. Baghdad; Iraq Headquarter of Copernicus Scientists International Panel Publishing: 2020.

Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, et al. Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys. Nature. 2016; 531(7594):381-385. https://doi.org/10.1038/nature17180

Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, et al. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med. 2017 Jun 28;9(396):eaal3653. https://doi.org/10.1126/scitranslmed.aal3653

Agostini ML, Andres EL, Sims AC, Graham RL, Sheahan TP, Lu X, et al. Coronavirus susceptibility to the antiviral remdesivir (gs-5734) is mediated by the viral polymerase and the proofreading exoribonuclease. mBio. 2018 Mar 6;9(2):e00221-18. https://doi.org/10.1128/mbio.00221-18

Pedersen NC, Perron M, Bannasch M, Montgomery E, Murakami E, Liepnieks M, et al. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis. J Feline Med Surg. 2019; 21(4):271-281. https://doi.org/10.1177/1098612x19825701

de Wit E, Feldmann F, Cronin J, Jordan R, Okumura A, Thomas T, et al. Prophylactic and therapeuticremdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6771-6776. https://doi.org/10.1073/pnas.1922083117

Wang Y, Zhang D, Du G, Du R, Zhao J, Jin Y, et al. Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. Lancet. 2020 May 16; 395(10236):1569-1578. https://doi.org/10.1016/s0140-6736(20)31022-9

Ansems K, Grundeis F, Dahms K, Mikolajewska A, Thieme V, Piechotta V, et al. Remdesivir for the Treatment of Covid-19. Cochrane Database Syst Rev. 2021 Aug 5;8(8):CD014962. https://doi.org/10.1056/NEJMoa2031994

Al-Mosawi AJ. Использование данных исследований для взлома замка SARS-CoV-2 (Russian edition) Sciencia Scripts: 2020. https://www.jelsciences.com/articles/jbres1181.pdf

Al-Mosawi AJ. Utilização de provas de investigação para rachar o cadeado da SRA-CoV-2 (Portuguese edition). Edições Nosso Conhecimento: 2020.

Al-Mosawi AJ. Użycie dowodów naukowych do złamania kłódki SARS-CoV-2 (Polish edition) Wnictwo Nasza Wiedza: 2020.

Al-Mosawi AJ. Gebruik van onderzoeksmateriaal voor het kraken van het hangslot van SARS-CoV-2 (Dutchedition). Uitgeverij Onze kennis: 2020.

Al-Mosawi AJ. Utilizzare le prove della ricerca per rompere il lucchetto della SARS-CoV-2 (Italian edition) Edizioni Sapien: 2020. https://doi.org/10.37871/jbres1146

Al-Mosawi AJ. Utilisation des résultats de la recherche pour briser le cadenas du SRAS-CoV-2. (French edition) Editions Notre Savoir: 2020.

Al-Mosawi AJ. El uso de pruebas de investigación para romper el candado del SARS-CoV-2 (Spanish edition). Ediciones Nuestro Conocimiento: 2020.

Al-Mosawi AJ. Verwendung von Forschungsergebnissen zum Knacken des Vorhängeschlosses von SARS-CoV-2. (German edition) Verlag Unser Vissen: 2020.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2020 Al Mosawi AJ