Triple Localized Cranio-Facial Fibrous Dysplasia: A Case Report

Abstract

Introduction: fibrous dysplasia of bones is a non-hereditary congenital benign bone disorder, where normal bone is replaced by pseudofibrous tissue containing immature osteogenesis.
Case report: a 29-year-old patient with chronic hemodialysis who had a swollen mouth and hard palate that had been evolving for a year, impeding chewing and swallowing and causing facial asymmetry. Cranio-facial CT revealed multiple osteolytic bone-blast lesions, the histopathological study of which favored polyostotic fibrous dysplasia.
Discussion: fibrous dysplasia lesions may be single or multiple and may be responsible for pain and fragility, causing neurological complications in craniofacial localization. Imaging and, when a biopsy is needed, histology can establish the diagnosis. The treatment is based on bisphosphonates or, in special cases, surgical excision.