Triple Localized Cranio-Facial Fibrous Dysplasia: A Case Report


Fibrous dysplasia - polyostotic - Craniofacial

How to Cite

Hamou M, Eabdenbitsen A, Elayoubi F, Ghailan MR. Triple Localized Cranio-Facial Fibrous Dysplasia: A Case Report. Integr J Med Sci [Internet]. 2019Mar.8 [cited 2021Jan.21];6. Available from:


Introduction: fibrous dysplasia of bones is a non-hereditary congenital benign bone disorder, where normal bone is replaced by pseudofibrous tissue containing immature osteogenesis.
Case report: a 29-year-old patient with chronic hemodialysis who had a swollen mouth and hard palate that had been evolving for a year, impeding chewing and swallowing and causing facial asymmetry. Cranio-facial CT revealed multiple osteolytic bone-blast lesions, the histopathological study of which favored polyostotic fibrous dysplasia.
Discussion: fibrous dysplasia lesions may be single or multiple and may be responsible for pain and fragility, causing neurological complications in craniofacial localization. Imaging and, when a biopsy is needed, histology can establish the diagnosis. The treatment is based on bisphosphonates or, in special cases, surgical excision.
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Copyright (c) 2019 Mahmoud Hamou et al.