Squamous Cell Carcinoma of the Lower Lip Arising in Discoid Lupus Lesion - A Case Report


Discoid lupus erythematosus
Squamous cell carcinoma

How to Cite

Sbai AA, Eabdenbitsen A, Elayoubi F, Ghailan MR. Squamous Cell Carcinoma of the Lower Lip Arising in Discoid Lupus Lesion - A Case Report. Integr J Med Sci [Internet]. 2018Feb.7 [cited 2021Mar.8];5. Available from: https://mbmj.org/index.php/ijms/article/view/113


Introduction : Rare examples from the literature report a possible degeneration of mucosal lesions of L.E.C. We report a case of squamous cell carcinoma grafted on a lesion of the lower lip in a patient followed for L.E.C. at the ENT and Maxillo-facial department of Mohamed VI University Hospital of Oujda.
Case report : A 47-year-old man, with a notion of photosensitivity, presents an atrophic erythematous-violet plaques in the photo-exposed zones evolving for 20 years, evoking chronic discoid lupus cutaneous without any clinical, biological or radiological sign of systematization. The patient had a painful lower ulcer-budding process that had been evolving for 2 years, with suspected bilateral cervical lymphadenopathy. The biopsy revealed a well-differentiated infiltrating squamous cell carcinoma. A surgical excision oncology is then performed with a labial plasty and an obviously bilateral lymph node. 
Conclusion : The risk of degeneration of skin lesions of lupus discoid is minimal and rare, although monitoring of lupus scars remains essential, especially in the context where exposure to ultraviolet radiation is added as a predisposing factor for possible malignant transformation, surgical treatment is required at the appearance of suspicious lesions confirmed histologically.

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Copyright (c) 2020 Achraf Amine Sbai et al.