Bilateral Adrenal Lymphoma: A Diagnostic Challenge


adrenal gland
image-guided biopsy


How to Cite

Kharbach Y, Rachidi Alaoui S, Bakkali Issaoui Z, Khallouk A. Bilateral Adrenal Lymphoma: A Diagnostic Challenge. Integr J Med Sci [Internet]. 2021 Jan. 15 [cited 2024 Jun. 15];8. Available from:


Bilateral primary adrenal lymphoma is rare with no specific clinical or imaging features. We report herein the case of a 44-year-old man presenting with massive bilateral adrenal tumors associated with normal adrenal function. Computed tomography findings were nonspecific. Because pheochromocytoma was ruled out and the patient had a normal coagulation test, we performed an ultrasound-guided adrenal biopsy for diagnostic purposes. Pathology confirmed adrenal non-Hodgkin's lymphoma. By reporting our case, we aimed to propose a practical approach for this rare entity and to show that there are still situations in which biopsy is necessary to make a diagnosis.


Laurent C, Casasnovas O, Martin L, Chauchet A, Ghesquieres H, Aussedat G, et al. Adrenal lymphoma: Presentation, management and prognosis. QJM. 2017;110:103‐9.

Lomte N, Bandgar T, Khare S, Jadhav S, Lila A, Goroshi M, et al. Bilateral adrenal masses: A single-centre experience. Endocr Connect. 2016; 5:92–100.

Rashidi A, Fisher SI. Primary adrenal lymphoma: A systematic review. Ann Hematol. 2013;92:1583–93.

Zhou L, Peng W, Wang C, Liu X, Shen Y, Zhou K. Primary adrenal lymphoma: Radiological, pathological, clinical correlation. Eur J Radiol. 2012;81:401–5.

Young WF Jr. Clinical practice. The incidentally discovered adrenal mass. N Engl J Med. 2007;356:601–10.

Gupta P, Bhalla A, Sharma R. Bilateral adrenal lesions. J Med Imaging Radiat Oncol. 2012; 56:636–45.

Sharma KV, Venkatesan AM, Swerdlow D, DaSilva D, Beck A, Jain N, et al. Image-guided adrenal and renal biopsy. Tech Vasc Interv Radiol. 2010; 13:100–9.

Ierardi AM, Petrillo M, Patella F, Biondetti P, Fumarola EM, Angileri SA, et al. Interventional radiology of the adrenal glands: Current status. GlandSurg. 2018; 7:147–65.

Alshahrani MA, Bin Saeedan M, Alkhunaizan T, Aljohani IM, Azzumeea FM. Bilateral adrenal abnormalities: Imaging review of different entities. Abdom Radiol NY. 2019; 44:154–79.

Gunna S, Neyaz Z, Bhatia E, Marak RS, Mishra R, Verma R. Results of percutaneous computedtomography-guided biopsy of adrenal lesions andspectrum of computed tomography findings. J Clin Imaging Sci. 2020; 10:16.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2021 Kharbach Y et al.


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