Vaginal Metastatic Recurrence of a Bladder Tumor after Anterior Pelvectomy – A Case Report


Urothelial carcinoma
Vaginal metastasis


How to Cite

Aboulaich Y, Kharbach Y, Khallouk A. Vaginal Metastatic Recurrence of a Bladder Tumor after Anterior Pelvectomy – A Case Report. Integr J Med Sci [Internet]. 2023 Aug. 28 [cited 2024 Jul. 24];10. Available from:


Background: Vaginal metastatic recurrence after anterior pelvic pelvectomy for bladder tumor is a rare occurrence that remains unexplained and requires specific recommendations to prevent or effectively treat it in a timely manner.
Case report: We report on a 69-year-old female patient with a history of hyperthyroidism who had undergone anterior pelvic pelvectomy for bladder tumor and presented a year later with vaginal bleeding. Gynecological examination with a speculum revealed four small budding tumors on the anterior vaginal wall. An anatomopathological study confirmed urothelial carcinoma. We performed surgical excision of all masses and complemented it with radiotherapy.
Conclusion: The purpose of our presentation is to discuss predictive factors for vaginal metastatic recurrence and to emphasize the importance of gynecological examination in follow-up after anterior pelvic pelvectomy, which we believe should be included in the recommendations for such follow-up.


Neuzillet Y, Audenet F, Loriot Y, Allory Y, Masson-Lecomte A, et al. French AFU Cancer Committee Guidelines-Update 2022-2024: Muscle-Invasive Bladder Cancer (MIBC). Progrès en Urologie. 2022;1141-63.

Colina P, Neuzillet Y, Pignot G, Rouprêt M, Comperat E, Larré S, et al. [Follow-up of urothelial carcinoma: Review of the cancer committee of the French Association of Urology]. Progrès en Urologie. 2015 Sep;25(10):616-24.

Lebret T, Méjean A. Rare locations of metastases from urothelial carcinoma. Progrès en Urologie. 2008;7:289-97.

Kasai T, Moriyama K, Tsuji M, Uema K, Sakurai N. [A case of vaginal implantation of transitional cell carcinoma of the bladder]. Jpnjurol. 2001;92:538-41.

Carmelo A, Di Franco D, Daniele P, Giovanni G, Alessandra V, Bruno R. Vaginal metastasis of bladder urothelial carcinoma. Archivio Italiano di Urologia e Andrologia. 2017 Jun 30;89(2):156-7.

Isono M, Ito K, Hamada S, Takahashi M, Sasa H, et al. Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report. Case Reports in Urology. 2018; 2018: 3069294.

Reyes MC, Park KJ, Lin O, et al. Urothelial Carcinoma Involving the Gynecologic Tract: A Morphologic and Immunohistochemical Study of 6 Cases. Am J Surg Pathol. 2012;36:1058–65.

Hong X, Li T, Ling F, Yang D, Hou L, et al. Impact of surgical margin status on the outcome of bladder cancer treated by radical cystectomy: a meta-analysis. Oncotarget. 2017;8:17258-69.

Chin JL, Wolf RM, Ruben RP, et al. Vaginal recurrence after cystectomy for bladder cancer. J Urol. 1985;134:58-61.

Sargos P, Baumann BC, Eapen L, Christodouleas J, Bahl A, et al. Risk factors for loco-regional recurrence after radical cystectomy of muscle-invasive bladder cancer: A systematic review and framework for adjuvant radiotherapy. Cancer Treat Rev. 2018;70:88-97.

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Copyright (c) 2023 Aboulaich Y et al.


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