Pulmonary Tuberculosis and Diabetes Mellitus Profile
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Keywords

Tuberculosis
Diabetes
Risk factor
Prevalence

How to Cite

1.
Kouismi H, Hammi S, Bouti K, Rhanim A, Ataouna K, Razine R, Bourkadi JE. Pulmonary Tuberculosis and Diabetes Mellitus Profile. Integr J Med Sci [Internet]. 2015Jun.30 [cited 2020Nov.25];2(1):11-5. Available from: https://mbmj.org/index.php/ijms/article/view/19

Abstract

Background : About 95% of patients with tuberculosis (TB) and 70% of patients with diabetes mellitus (DM) live in low and middle-income countries. As a result, DM and TB are increasingly occurring together. The risk of tuberculosis is two to five times greater in patients with diabetes.The purpose of this study is to analyze the characteristics of pulmonary tuberculosis in patients with diabetes and to evaluate the impact of tuberculosis on diabetes control.
Patients and Methods : This is a retrospective study of 80 patients with confirmed pulmonary tuberculosis, comparing 30 patients with diabetes with 50 without diabetes.
Results : Diabetes was more frequent in older patients with tuberculosis and in male patients. 63,3% had type 2 diabetes. Tuberculosis symptoms did not differ between the two groups. Involvement of basal segments of the lower lobes and cavitation occurred more frequently in patients with diabetes, but this difference was not significant. The time for conversion to negative of sputum culture was longer in control patients (44,1 ± 20,2 days) than in case (36 ± 18.3) (p = 0.08).
Conclusion : Tuberculosis is frequently associated with diabetes mainly in low-income countries. The problem with this association could be accentuated in the future.

https://doi.org/10.15342/ijms.v2i1.68
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References

Banerjee S, Banerjee M. Diabetes and tuberculosis interface. J Indian Med Assoc 2005;103:318,320,322 passim.

Jeon CY,Murray MB. Diabetes mellitus increases the risk of active tuberculosis: a systematic review of 13 observational studies.PLoS Med 2008;5:e152.

Soundararajan Raghuraman, Kavita P Vasudevan, S Govindarajan, Palanivel Chinnakali, and Krishna Chandra Panigrahi. Prevalence of Diabetes Mellitus among Tuberculosis Patients in Urban Puducherry. N Am J Med Sci. Jan 2014; 6(1): 30–34.

Touré NO, Dia Kane Y, Diatta A, Ba Diop S, Niang A, Ndiaye EM et al. Tuberculose et diabète. Rev Mal Repir 2007;24:869-75.

Wang CS, Chen HC,Yang CJ, Tsai JR, Chong LW, Hwang JJ et al. Clinical characteristics of pulmonary tuberculosis patients from a southern Taiwan hospital-based survey. Kaohsiung J Med Sci. 2008; 24: 17–24

Stevenson CR, Forouhi NG, Roglic G, Williams BC, Lauer JA, Dye C et al. Diabete and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. BMC Public Health 2007;7:234.

Stevenson CR, Forouhi NG, Roglic G et al. Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. BMC Public Health 2007;7:234.

Mugusi F, Swai AB, Alberti KG, McLarty DG. Increased prevalence of diabetes mellitus in patients with pulmonary tuberculosis in Tanzania. Tubercle 1990;71:271–6.

Pérez-Guzmàn C, Torres-Cruz A, Villarreal- Velarde H, Salazar-Lezama MA, Vargas MH. Atypical radiological images of pulmonary tuberculosis in 192 diabetic patients: a comparative study. Int J Tuberc Lung Dis 2001;5(5):455-61.

Mboussa J, Monabeka H, Kombo M, Yokolo D, Yoka-Mbio D, Yala F. Évolution de la tuberculose pulmonaire chez les diabétiques. Rev Pneumol Clin 2003;59:39-44.

Sonia Maâlej, Nachraouane Belhaoui, Mehrezia Bourguiba, Ridha Mahouachi, Amel Chtourou, Sofia Taktak, Hamouda Fennira, Leila Slim, Ali Ben Kheder, Ikram Drira. La tuberculose pulmonaire provoque un déséquilibre du diabète. Étude rétrospective de 60 malades en Tunisie. Presse Med. 2009; 38: 20–24

Guptan A, Shah A. Tuberculosis and Diabetes: An Appraisal. Ind J Tub. 2000;47(3):2–8.

Ponce-De-Leon A, Garcia-Garcia Md Mde L, Garcia-Sancho MC, Gomez-Perez FJ, Valdespino-Gomez JL, Olaiz-Fernandez G, et al. Tuberculosis and diabetes in southern Mexico. Diabetes Care. 2004;27:1584–90. [PubMed: 1522

Alisjahbana B, Sahiratmadja E, Nelwan EJ, Purwa AM, Ahmad Y, Ottenhoff TH, et al. The effect of type 2 diabetes mellitus on the presentation and treatment response of pulmonary tuberculosis. Clin Infect Dis. 2007;45:428–35. [PubMed: 17638189]

N. M. Baldé, A. Camara, L. M. Camara, M. M. Diallo, A. Kaké, O. Y. Bah-Sow. Tuberculose et diabète à Conakry, Guinée : prévalence et caractéristiques cliniques de l’association. Int J Tuberc Lung Dis 10(9): 1036-1040 © 2006 The Union

Feleke Y, Abdulkadir J, Aderaye G. Prevalence and clinical features of tuberculosis in Ethiopian diabetic patients. East Afr Med J 1999; 76: 361-364.

Ezung T, Devi N T, Singh N T, Singh T B. Pulmonary tuberculosis and diabetes mellitus—a study. J Indian Med Assoc 2002; 100: 378-379.

Kelly E Dooley and Richard E Chaisson. Tuberculosis and diabetes mellitus: convergence of two epidemics. Lancet Infect Dis. 2009 December ; 9(12): 737–746. doi:10.1016/S1473-3099(09)70282-8.

Wang CS, Yang CJ, Chen HC et al. Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis. Epidemiol Infect 2009;137:203–10.

Nissapatorn V, Kuppusamy I, Jamaiah I et al. Tuberculosis in diabetic patients: a clinical perspective. Southeast Asian J Trop Med Public Health 2005;36(Suppl 4):213–20.

Sosman M, Steidl J. Diabetic tuberculosis. Am J Roentgenol 1927;17:625.

Weaver RA. Unusual radiographic presentation of pulmonary tuberculosis in diabetic patients. Am Rev Respir Dis 1974;109:162–63.

Marais RM. Diabetes mellitus in black and coloured tuberculosis patients. S Afr Med J 1980;57:483– 84.

Perez-Guzman C, Torres-Cruz A, Villarreal H, Vargas MH. Progressive agerelated changes in pulmonary tuberculosis images and the effect of diabetes. Am J Respir Crit Care Med 2000; 162:1738-40.

Bacakoglu F, Kaçmaz Basoglu O, Cok G, Saymer A, Ates M. Pulmonary tuberculosis in patients with diabetes mellitus. Respiration 2001; 68:595-600.

Nissapatorn V, Kuppusamy I, Jamaiah I, Fong MY, Rohela M, Anuar K. Tuberculosis in diabetic patients: A clinical perspective. Southeast Asian J Trop Med Public Health 2005; 36(4):213-20.

Mboussa J, Monabeka H, Kombo M, Yokolo D, Yoka-Mbio A, Yala F. Course of pulmonary tuberculosis in diabetics. Rev Pneumol Clin 2003;59:39–44.

Wang CS, Yang CJ, Chen HC, et al. Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis. Epidemiol Infect 2009;137:203–10.

Hendy M, Stableforth D. The effect of established diabetes mellitus on the presentation of infiltrative pulmonary tuberculosis in the immigrant Asian community of an inner city area of the United Kingdom. Br J Dis Chest 1983;77:87–90.

Singla R, Khan N, Al-Sharif N, Ai-Sayegh MO, Shaikh MA, Osman MM. Influence of diabetes on manifestations and treatment outcome of pulmonary TB patients. Int J Tuberc Lung Dis 2006;10(1):74-9.

Banu Rekha VV, Balasubramaniam R, Swaminathan S, Ramachandran R, Rahman F. Sputum conversion at the end of intensive phase of category-1 regim in treatment of pulmonary tuberculosis patients with diabetes mellitus or HIVinfection: An analysis of risk factors. Indian J Med Res 2007;126: 452-8.

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